Vasorelaxant Effects of Pramanicin, an Anti-fungal Agent: Selective Action on Endothelial Cells
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چکیده
منابع مشابه
Vasorelaxant effects of pramanicin, an anti-fungal agent: selective action on endothelial cells.
A newly discovered antifungal agent, pramanicin, within the therapeutically effective concentration range (4-100 microM), inhibits the tone of phenylephrine (PE)-precontracted dog carotid arterial rings in a concentration-dependent manner and leads to gradual development of relaxation. However, pramanicin had no effect on rings precontracted with 100 mM KCl or on endothelium-denuded rings. Thus...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 2001
ISSN: 0021-5198
DOI: 10.1254/jjp.85.234